Hypertension, Diabetes, Dyslipidemia and Obesity are considered as major risk factors for Atherosclerosis of cerebral, coronary and peripheral arteries. This process causes Development of Ischemic heart disease, obstruction to cerebral flow and PVD. Clustering of these risk factors is very common and their accumulation causes faster propagation of end organ damage and cerebrovascular events. The diagnosis of risk factors, especially when they are clustered, justify multidisciplinary aggressive therapeutic approach which should be started as soon as possible with the diagnosis. |